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Glucosamine Sulfate Combined with Tumeric Extract, Manganese, Vitamin C, and Silicon Represent the Most Powerful Blend for Joint Health

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One of the most highly sought nutritional products is glucosamine. Many who are in search of this nutritional are looking for joint pain relief. What they may not realize is that taking this alone is not the solution. They may not be aware that in order for this to help your actual joints it must be absorbed into your bloodstream properly. This works better when working in combination with tumeric acid and vitamin c, silicon, and manganese. This provides a more comprehensive approach to joint health.

Let go into a little more detail. Everyday your joints endure an enormous amount of stress from physical activity, lifting, and walking. We expect them to function properly and take them for granted. However, the truth is that 50 million people in the United States alone and 6 million more in Canada suffer from some form of joint problem. The numbers are worse for athletes and those who place an inordinate amount of added stress on their joints.

To help support healthy joints we need the proper blend of glucosamine, manganese, vitamin c, and silicon. These are the proper building blocks for healthy cartilage.


Cartilage is the protective layer that protects and lubricates the joint. Over the years, the cartilage wears down due to normal activity. The body can rebuild the cartilage as it’s worn down. It can replace the synovial fluid which acts as a shock absorber. However, for various reasons it can be fall behind in demand. Poor blood supply further complicates matters because lesions to articular cartilage do not heal at the same rate as other tissues in the body. Cartilage needs time to be rebuilt. If they don’t have the right building blocks and are short in supply the recovery from damage can take even longer and require more time.



This is where glucosamine comes into the picture. It is an amino sugar and an important precursor in the biosynthesis of cartilage. It is a building block of proteoglycans which are essentially protein molecules. (1) This in combination with collagen composes the majority of what we call cartilage. When cartilage degenerates, we feel joint pain and osteoarthritis may result.

In addition it is believed to play a role in normalizing cartilage metabolism by encouraging the production of hyaluronic acid which is responsible for producing the shock absorbing properties of synovial fluid. (3) It is plays a role by encouraging higher production of collagen and proteoglycans. (2)

There are numerous studies that support the efficacy of these supplements in maintaining healthy cartilage, and healthy joints. This in turn translates to no pain and full range of motion in the short-term. (4-10) A three -year study was published that showing that joint space increased in the glucosamine-treated placebo group, indicating that the protective cartilage was better maintained in those who used it. (11) Additional studies have shown that taking glucosamine orally, is well-absorbed and diffuses into tissues including the articular cartilage. (12-14)



So why the powerful blend that I recommended above? The answer is because it is the most comprehensive approach to joint health. Glucosamine sulfate promotes the incorporation of sulfur, a component of protein into the cartilage matrix. Turmeric contains curcumin and related compounds known as curcuminoids, which have good antioxidant properties. (15-16) Manganese is required for enzymes involved in the biosynthesis of proteoglycans. (17-18) Vitamin C is essential for the reactions necessary for collagen formations. Finally, silicon is required for proper collagen formation as well as cartilage composition. (19)

I supplement with a joint formula every single day since I had a herniated disc in my back. Today I can run and play ball with my 5 year old son.

Click here for more scientific information on glucosamine.

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References

1. Karzel K, Domenjoz R. Pharmacology 1971;5:337-45.
2. Goggs, R, et al. Crit Rev Food Sci Nutr 2005;45(3):145-64.
3. Matheson AJ, Perry CM. Drugs Aging 2003;20(14):1041-60.
4. Pujalte JM, et al. Curr Med Res Opin 1980;7:110-14.
5. Lopes VA. Curr Med Res Opin 1982;8:145-49.
6. Muller-Fassbender, et al. Osteoarth Cartilage 1994;2:61-69.
7. Crolle G, D’Este E. Curr Med Res Opin 1980;7:104-09.
8. Dovanti A, et al. Clin Therapeutics 1980;3:266-72.
9. Pujalte JM, et al. Curr Med Res Opin 1980;7:110-14.
10. Tapadinhas MJ, et al. Pharmatherapeutica 1982;3:157-68.
11. Reginster JY, et al. Lancet 2001;357:251-56.
12. Vaz AL. Curr Med Res Opin 1982;8:145-49.
13. Fabender H, et al. Osteoarthr and Cartilage 1994;2:61-69.
14. D’Ambrosio E, et al. Pharmatherapeutica 1981;1:504.
15. Maheshwari RK, et al. Life Sci 2006;78(18):2081-7.
16. Sreejayan R. J Pharm Pharmacol 1994;46:1013-16.
17. Tinker D, Rucker RB. Physiol Rev 1985;65(3):607-57.
18. Yang P, Klimis-Tavantzis DJ. Biol Trace Elem Res 1998;64(1-3):275-88.
19. Bisse E, et al. Anal Biochem 2005;337(1):130-5.


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